Imagine feeling the positive sensations of a couple of cocktails—you know, increased joviality, decreased inhibitions and so on—without the consequential hangover the next day. Scientists are currently developing a cocktail of drugs that will elicit the pleasurable effects of drinking without the slurred speech and spinning head that usually accompany imbibing. Drugs are a poor substitution for a full-bodied glass of cabernet or a cold beer, but the idea is still intriguing the scientific community. Psychopharmacologist David Nutt of the University of Bristol will publish the idea in next month's Journal of Psychopharmacology.